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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD1A
All Species:
28.79
Human Site:
Y1623
Identified Species:
48.72
UniProt:
O15047
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15047
NP_055527.1
1707
186034
Y1623
Q
E
G
I
G
S
S
Y
L
F
R
V
D
H
D
Chimpanzee
Pan troglodytes
XP_523492
1707
185692
Y1623
Q
E
G
I
G
S
S
Y
L
F
R
V
D
H
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848999
1330
145541
L1247
E
G
I
G
S
S
Y
L
F
R
V
D
H
D
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFT2
1985
215333
Y1901
D
E
G
I
G
S
S
Y
M
F
R
V
D
H
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506028
1287
141359
M1204
E
G
I
G
S
S
Y
M
F
R
V
D
H
D
T
Chicken
Gallus gallus
Q5F3P8
2008
223067
Y1924
D
E
G
I
G
S
S
Y
M
F
R
V
D
H
D
Frog
Xenopus laevis
Q66J90
1938
216239
Y1854
D
E
G
I
G
S
S
Y
M
F
R
V
D
H
D
Zebra Danio
Brachydanio rerio
Q1LY77
1844
204122
Y1760
D
E
G
I
G
S
S
Y
M
F
R
V
D
H
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015221
1641
188364
Y1557
A
I
G
I
G
S
S
Y
L
F
R
I
D
M
E
Honey Bee
Apis mellifera
XP_395451
1406
159180
L1323
T
G
I
G
S
S
Y
L
F
R
I
D
L
D
T
Nematode Worm
Caenorhab. elegans
Q18221
1507
171664
L1424
R
G
I
G
S
S
Y
L
F
R
I
D
L
H
H
Sea Urchin
Strong. purpuratus
XP_791552
1963
220543
Y1879
R
M
G
I
G
S
S
Y
L
F
R
I
D
A
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38827
1080
123894
V997
G
S
S
Y
L
F
R
V
D
E
N
T
V
I
D
Red Bread Mold
Neurospora crassa
Q8X0S9
1313
145607
I1230
G
S
S
Y
L
F
R
I
D
D
N
T
V
I
D
Conservation
Percent
Protein Identity:
100
99.5
N.A.
73.2
N.A.
37
N.A.
N.A.
27.7
34.5
34.1
36.7
N.A.
25.6
24.6
20.9
23.7
Protein Similarity:
100
99.5
N.A.
74.7
N.A.
49.5
N.A.
N.A.
38.7
47.5
48.6
50.7
N.A.
41.3
39.6
35.8
39.2
P-Site Identity:
100
100
N.A.
6.6
N.A.
86.6
N.A.
N.A.
6.6
86.6
86.6
86.6
N.A.
66.6
6.6
13.3
66.6
P-Site Similarity:
100
100
N.A.
13.3
N.A.
93.3
N.A.
N.A.
13.3
93.3
93.3
93.3
N.A.
80
6.6
20
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.7
22.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
33.8
36.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
29
0
0
0
0
0
0
0
15
8
0
29
58
22
58
% D
% Glu:
15
43
0
0
0
0
0
0
0
8
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
15
0
0
29
58
0
0
0
0
0
% F
% Gly:
15
29
58
29
58
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
15
50
8
% H
% Ile:
0
8
29
58
0
0
0
8
0
0
15
15
0
15
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
15
0
0
22
29
0
0
0
15
0
0
% L
% Met:
0
8
0
0
0
0
0
8
29
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
15
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
15
0
0
0
0
0
15
0
0
29
58
0
0
0
0
% R
% Ser:
0
15
15
0
29
86
58
0
0
0
0
0
0
0
0
% S
% Thr:
8
0
0
0
0
0
0
0
0
0
0
15
0
0
22
% T
% Val:
0
0
0
0
0
0
0
8
0
0
15
43
15
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
15
0
0
29
58
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _